How MICE design methodology can be used in e- commerce environment? As known, most of companies have web sites, and they serve some services using these pages. Most of these pages need interactive action. Using CGI programs performs these actions. These programs should be prepared by using different techniques. MICE environment also can be used to realize the active systems in e-commerce. In this study, active index system approach was applied to make reservation and to buy an airline ticket in optimum price as an example.